Publications

(*): co-first authorship; (†): corresponding author

2025

DeepTarget predicts anti-cancer mechanisms of action of small molecules by integrating drug and genetic screens

DeepTarget predicts anti-cancer mechanisms of action of small molecules by integrating drug and genetic screens

Sanju Sinha, Neelam Sinha, Marlenne Perales, Adi Tarrab, Trinh Nguyen, Lihe Liu, and

npj Precision Oncology 2025

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EnrichKit: a multi-omics tool for livestock research

EnrichKit: a multi-omics tool for livestock research

Lihe Liu†, Francisco Peñagaricano†

Frontiers in Genetics 2025

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Preweaning heat stress alters liver transcriptome and DNA methylation in dairy calves

Preweaning heat stress alters liver transcriptome and DNA methylation in dairy calves

Jimena Laporta, Bethany Dado-Senn, Anne R Guadagnin, Lihe Liu, Francisco Peñagaricano

Journal of Dairy Science 2025

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2024

The metabolomic composition of the oviductal fluid is controlled by the periovulatory hormonal context in Bos indicus cows

The metabolomic composition of the oviductal fluid is controlled by the periovulatory hormonal context in Bos indicus cows

Angela Gonella-Diaza, Mariana Sponchiado, Moana Rodrigues França, Lihe Liu, Guilherme Pugliesi, Edson Guimarães Lo Turco, and

Biology of Reproduction 2024

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ecPath detects ecDNA in tumors from histopathology images

ecPath detects ecDNA in tumors from histopathology images

Mudra Choudhury*, Lihe Liu*, Anamika Yadav, Owen Chapman, Zahra Ahmadi, Raneen Younis, and

bioRxiv 2024 (Under review)

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2023

Maternal diet induces persistent DNA methylation changes in the muscle of beef calves

Maternal diet induces persistent DNA methylation changes in the muscle of beef calves

Rocío Amorín*, Lihe Liu*, Philipe Moriel, Nicolás DiLorenzo, Phillip Lancaster, Francisco Peñagaricano

Scientific Reports 2023

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2022

Impact of fluoxetine treatment and folic acid supplementation on the mammary gland transcriptome during peak lactation

Impact of fluoxetine treatment and folic acid supplementation on the mammary gland transcriptome during peak lactation

Celeste Sheftel, Lihe Liu, Sena Field, Samantha Weaver, Chad Vezina, Francisco Peñagaricano, and

Frontiers in Pharmacology 2022

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2021

Maternal methionine supplementation during gestation alters alternative splicing and DNA methylation in bovine skeletal muscle

Maternal methionine supplementation during gestation alters alternative splicing and DNA methylation in bovine skeletal muscle

Lihe Liu, Rocío Amorín, Philipe Moriel, Nicolás DiLorenzo, Phillip A Lancaster, Francisco Peñagaricano

BMC genomics 2021

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Effect of natural pre-luteolytic prostaglandin F2α pulses on the bovine luteal transcriptome during spontaneous luteal regression†

Effect of natural pre-luteolytic prostaglandin F2α pulses on the bovine luteal transcriptome during spontaneous luteal regression†

Megan Mezera, Wenli Li, Lihe Liu, Rina Meidan, Francisco Peñagaricano, Milo Wiltbank

Biology of Reproduction 2021

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Histological and transcriptomic analysis of adipose and muscle of dairy calves supplemented with 5-hydroxytryptophan

Histological and transcriptomic analysis of adipose and muscle of dairy calves supplemented with 5-hydroxytryptophan

Sena Field, Marcela Marrero, Lihe Liu, Francisco Peñagaricano, Jimena Laporta

Scientific Reports 2021

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2020

Differential network analysis of bovine muscle reveals changes in gene coexpression patterns in response to changes in maternal nutrition

Differential network analysis of bovine muscle reveals changes in gene coexpression patterns in response to changes in maternal nutrition

Lihe Liu, Rocío Amorín, Philipe Moriel, Nicolás DiLorenzo, Phillip A Lancaster, Francisco Peñagaricano

BMC genomics 2020

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Genetic dissection of reproductive performance of dairy cows under heat stress

Genetic dissection of reproductive performance of dairy cows under heat stress

Anil Sigdel, Lihe Liu, Rostam Abdollahi‐Arpanahi, Ignacio Aguilar, Francisco Peñagaricano

Animal genetics 2020

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Gestational and lactational exposure to gossypol alters the testis transcriptome

Gestational and lactational exposure to gossypol alters the testis transcriptome

Helder Louvandini, Patricia S. Corrêa, Rocío Amorín, Lihe Liu, Egon H. Ieda, Carolina R. Jimenez, and

BMC genomics 2020

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